Nga korero taketake
Ingoa Hua | Putumōhio | Momo | Kaihautū/Pūtake | Whakamahinga | Nga tono | Epitope | COA |
HCV Core-NS3-NS5 fusion antigen | BMIHCV203 | Antigen | E.coli | Hopu | CMIA,WB | / | Tikiake |
HCV Core-NS3-NS5 fusion antigen | BMIHCV204 | Antigen | E.coli | Whakakotahi | CMIA,WB | / | Tikiake |
HCV Core-NS3-NS5 fusion antigen-Bio | BMIHCVB02 | Antigen | E.coli | Whakakotahi | CMIA,WB | / | Tikiake |
HCV Core-NS3-NS5 fusion antigen | BMIHCV213 | Antigen | HEK293 Pūtau | Whakakotahi | CMIA,WB | / | Tikiake |
Ko te pathogenesis o te mate hepatitis C kare tonu i te marama.Ka huri te HCV i roto i nga pūtau ate, ka puta he huringa i roto i te hanganga me te mahi o nga pūtau ate, ka pokanoa ranei ki te whakahiato o nga pūmua ate ate, ka taea te whakaheke me te necrosis o nga pūtau ate, e tohu ana ko te HCV ka pakaru tika i te ate me te whai waahi ki te pathogenesis.Heoi, he maha nga tohunga pangarau e whakapono ana ka whai waahi nui te tauhohenga immunopathological o te waea.I kitea e ratou ko te mate hepatitis C, penei i te mate hepatitis B, te nuinga o nga pūtau whakauru CD3+ i roto i ona kopa.Ko nga pūtau T Cytotoxic (TC) ka tino whakaekea nga pūtau whainga o te mate HCV, ka taea te kino o nga pūtau ate.
RIA or ELISA
I whakamahia te Radioimmunodiagnosis (RIA) me te whakamaarama immunosorbent hono-e-enema (ELISA) kia kitea te anti HCV i roto i te serum.I te tau 1989, ko Kuo et al.i whakaritea he tikanga radioimmunoassay (RIA) mo te anti-C-100.I muri mai, i angitu a Ortho Kamupene ki te hanga i tetahi whakamatautau immunosorbent e hono ana i te enzyme (ELISA) kia kitea te anti-C-100.Ko nga tikanga e rua e whakamahi ana i te rewena recombinant e whakaatu ana i te antigen huaketo (C-100-3, he pūmua e whakawaeheretia ana e NS4, kei roto 363 waikawa amino), i muri i te purenga, ka pania ki te iti o nga kohao pereti kirihou, ka taapiri atu ki te serum kua whakamatauria.Ko te antigen huaketo ka honoa ki te anti-C-100 i roto i te serum kua whakamatauria.Ka mutu, ka taapirihia te isotope me te enzyme kiore e tohu ana i te antibody antibody lgG monoclonal antibody, ka taapirihia te tïpako hei whakatau i te tae.